Considering a trial involving groups or clusters?
Check out NIH's Research Methods Resources website.
Part 3 explores power and sample size for group-randomized trials (GRTs), individually randomized group-treatment (IRGT) trials, and stepped wedge group-randomized trials (SWGRTs). It introduces resources from NIH's Research Methods Resources website that can be used for power and sample size estimation in these designs and provides a brief tutorial for sample size estimation in a parallel GRT.