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Part of the mission of the Office of Disease Prevention (ODP) is to disseminate the results of high-quality, evidence-based disease prevention research. To facilitate the dissemination and use of evidence-based interventions, the ODP has identified several databases and other resources that provide information on evidence-based disease prevention services, programs, and practices with the potential to impact public health.

What does it mean for something to be evidence-based?

To ensure that high-quality disease prevention research is being used to improve the health of all Americans, it is important to apply the best available research results (evidence) when making decisions and designing programs and interventions. Sources of evidence about prevention services, programs, and practices include clinical trials and observational studies. A body of evidence on a given topic is often evaluated by conducting a systematic review and/or meta-analysis, which can inform decisions about whether to provide a prevention service or program. Each agency and organization represented in the list below used their own processes to identify evidence-based services, programs, and practices. To be included in this list, websites must: identify multiple evidence-based interventions that span a range of topic areas, be available free of charge, be easily accessible, and provide detailed information about the interventions listed.

List of Evidence-Based Strategies and Interventions

The websites listed below—which are sponsored by various government agencies, non-profit organizations, and private-sector organizations—provide information about evidence-based services, programs, and best practices. The resources are intended for a range of audiences, including community planners and implementers, health care and public health professionals, policymakers, researchers, and the general public.

Blueprints for Healthy Youth Development

Hosted by the Center for the Study and Prevention of Violence (CSPV), University of Colorado Boulder
Funded by the Annie E. Casey Foundation

Blueprints for Healthy Youth Development External Website Policy provides a registry of evidence-based positive youth development programs designed to promote the health and well-being of children and teens. Blueprints programs are family-, school-, and community-based and target all levels of need—from broad prevention programs that promote positive behaviors while decreasing negative behaviors, to highly targeted programs for at-risk children and troubled teens that aim to get them back on track. These resources are intended for community planners/implementers, health care professionals, policymakers/decision-makers, and researchers.

Community Health Online Resource Center

Division of Community Health (DCH), Centers for Disease Control and Prevention (CDC)

The Community Health Online Resource Center provides a collection of tools to support environmental changes that address obesity and tobacco use. The Center’s resources describe why environmental changes are at the heart of making healthy living easier, and how to execute them. Tools include webinars, model policies, tool kits, databases, fact sheets, and other practical materials. These resources are intended for community planners/implementers, health care professionals, policymakers/decision-makers, and researchers.

CrimeSolutions.gov

Office of Justice Programs (OJP), Department of Justice (DOJ)

CrimeSolutions.gov uses rigorous research to determine which preventive interventions work in criminal justice, juvenile justice, and crime victim services. CrimeSolutions.gov presents reviews of justice programs and justice practices (e.g., activities, strategies, procedures). These resources are intended for health care professionals and policymakers/decision-makers.

Effective Interventions — HIV Prevention that Works

Centers for Disease Control and Prevention (CDC)

Effective Interventions — HIV Prevention That Works provides information on evidence-based biomedical, behavioral, and structural interventions, public health strategies, and social marketing tools that help prevent HIV/AIDS among persons at risk for acquiring or transmitting HIV. These resources are intended for HIV prevention providers such as health departments and community-based organizations.

Electronic Preventive Services Selector (ePSS)

Agency for Healthcare Research and Quality (AHRQ)

The Electronic Preventive Services Selector (ePSS) is a quick, hands-on tool designed to help primary care clinicians and health care teams identify, prioritize, and deliver the screening, counseling, and preventive medication services that are appropriate for their patients. The ePSS is based on the current, evidence-based recommendations of the U.S. Preventive Services Task Force (USPSTF). These resources are intended for the public, health care professionals, and policymakers/decision-makers.

Healthy People 2020 Evidence-Based Resources

Office of Disease Prevention and Health Promotion (ODPHP), Department of Health and Human Services (HHS)

Healthy People 2020 provides a science-based, 10-year agenda for improving the health of all Americans. This searchable database contains hundreds of evidence-based interventions and resources to improve the health of communities. These resources are intended for the public, community planners/implementers, health care professionals, policymakers/decision-makers, and researchers.

National Registry of Evidence-based Programs and Practices (NREPP)

Substance Abuse and Mental Health Services Administration (SAMHSA)

The National Registry of Evidence-based Programs and Practices (NREPP) is a searchable online database with summaries on hundreds of mental health and substance abuse interventions. The purpose of NREPP is to help the public learn more about available evidence-based programs and practices and determine which of these may best meet their needs.

Prevention Strategies – CDC's Winnable Battles

Prevention Research Center (PRC), Centers for Disease Control and Prevention (CDC)

Winnable Battles are a collection of case studies on public health priorities and effective prevention strategies to address them. The prevention strategies were research-tested by a national network of Prevention Research Centers to improve communities’ health. These resources are intended for the public, community planners/implementers, health care professionals, policymakers/decision-makers, and researchers.

Research-Tested Intervention Programs (RTIPs)

National Cancer Institute (NCI), National Institutes of Health (NIH)

Research-Tested Intervention Programs (RTIPs) is a searchable database of cancer control interventions and program materials designed to provide program planners and public health practitioners easy and immediate access to research-tested materials. These resources are intended for community planners and health care professionals.

Teen Pregnancy Prevention Resource Center: Evidence-Based Programs Database

Office of Adolescent Health (OAH), Department of Health and Human Services (HHS)

This searchable Evidence-Based Programs Database contains programs, identified by the Teen Pregnancy Prevention Evidence Review, shown to be effective at preventing teen pregnancies, sexually transmitted infections, or sexual risk behaviors. These resources are intended for community planners, health care professionals, policymakers/decision-makers, and researchers.

The Guide to Community Preventive Services (The Community Guide)

Centers for Disease Control and Prevention (CDC)

The Guide to Community Preventive Services (The Community Guide) is a collection of evidence-based findings External Website Policy of the Community Preventive Services Task Force (Task Force) External Website Policy. It is a resource to help decisionmakers select interventions to improve health and prevent disease within states, communities, organizations, businesses, health systems, and schools. The Task Force uses rigorous systematic reviews External Website Policy and information about local needs, goals, and constraints to develop evidence-based recommendations for the public health community.

Top Tier Evidence Initiative

Hosted by the Coalition for Evidence-Based Policy
Funded by the MacArthur Foundation

The Top Tier Evidence Initiative External Website Policy provides public officials with strong, replicated evidence of the effectiveness of social interventions aimed at preventing educational and workforce failure, child abuse, teen pregnancy, crime, and other problems that burden millions of Americans each year. These resources are intended for community planners/implementers and policymakers/decision-makers.

U.S. Preventive Services Task Force (USPSTF)

Agency for Healthcare Research and Quality (AHRQ)

The U.S. Preventive Services Task Force External Website Policy (USPSTF) is an independent panel of non-federal experts in prevention and evidence-based medicine that works to improve the health of all Americans by making evidence-based recommendations about clinical preventive services such as screening, counseling, and preventive medications. The USPSTF conducts scientific evidence reviews of a broad range of clinical preventive health care services and develops recommendations for primary care clinicians and health systems. The USPSTF assigns each recommendation External Website Policy a letter grade External Website Policy (an A, B, C, D, or I) based on the strength of the evidence and the balance of benefits and harms of a preventive service. The USPSTF recommendation statements are receiving increased public notice as the Affordable Care Act mandates that A and B recommendations are adopted and covered by Medicare and private insurers within a year of their release.

What Works Clearinghouse (WWC)

Institute of Education Sciences (IES), Department of Education (ED)

The What Works Clearinghouse (WWC) aims to help educators and policymakers choose appropriate, evidence-based education products and curricula. The WWC identifies studies that provide credible and reliable evidence of the effectiveness of a given practice, program, or policy and disseminates summary information and free reports. With hundreds of publications available and more than 10,000 reviewed studies in the online searchable database, the WWC aims to inform researchers, educators, and policymakers as they work toward improving education for students. These resources are intended for community planners/implementers, policymakers/decision-makers, and researchers.

The ODP is not responsible for the accessibility or content of these websites and does not endorse, warrant, or guarantee accuracy of the information described or offered by private organizations.