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Funding

Funding Opportunities

Search a list of federal notices of funding opportunities (NOFOs) related to prevention research. You can filter by topic area or research method. For a list of all active funding opportunities and notices or to find records of funding opportunities that expired more than 5 years ago, please visit the NIH Guide for Grants and Contracts.

August 2025 — Important Announcements About Finding NIH Funding Opportunities

NIH Will Stop Posting Notices of Funding Opportunities in the NIH Guide for Grants and Contracts in FY2026 (NOT-OD-25-143): Beginning October 2025, NIH will no longer post notices of funding opportunities in the NIH Guide for Grants and Contracts. Grants.gov will serve as NIH’s single official source for grant and cooperative agreement funding opportunities. The NIH Guide will continue to be used for policy and informational notices.
Updates to Finding NIH Funding Opportunities and Information: NIH has several efforts underway that will change how potential applicants learn about scientific topics of specific interest to NIH and find grant and cooperative agreement funding opportunities in fiscal year 2026. These efforts are part of a wider strategy across NIH to simplify and streamline the application and funding process. These efforts include consolidating funding-related information currently distributed across NIH institute, center, and office websites on to the NIH Grants & Funding site.

Title

NOFO Number

Expiration Date

Showing 1 - 7 of 7 Results

High Priority HIV and Substance Use Research (RM1 Clinical Trial Optional)

NOFO Number

Release Date

01/17/2024

Expiration Date

Expiration Date

02/11/2027

Type of Award

Clinical Trials

Clinical Trial Optional

Organizations

Categories

Infectious Disease,

Methods Development,

Systems Science,

Dissemination and Implementation,

Health Disparities

Archived

No

HEAL Initiative: Research to Foster an Opioid Use Disorder Treatment System Patients Can Count On (RM1 - Clinical Trial Optional)

NOFO Number

Release Date

07/06/2022

Expiration Date

Expiration Date

02/03/2023

Type of Award

Clinical Trials

Clinical Trial Optional

Organizations

Categories

Methods Development,

Dissemination and Implementation,

Archived

Yes

Notice of Special Interest: Research on Pain, Pain Management, and Opioids in Aging

NOFO Number

Release Date

12/22/2021

Expiration Date

Expiration Date

01/08/2025

Type of Award

Clinical Trials

Clinical Trial Optional,

Clinical Trial Not Allowed,

Basic Experimental Studies with Humans (BESH) Required,

Clinical Trial Required

Organizations

Categories

Methods Development

Archived

Yes

Notice of Special Interest (NOSI): Advancing HIV/AIDS Research through Computational Neuroscience

NOFO Number

Release Date

06/22/2021

Expiration Date

Expiration Date

01/08/2025

Type of Award

Clinical Trials

Clinical Trial Optional

Organizations

Categories

Infectious Disease,

Big Data Science,

Methods Development

Archived

Yes

Notice of Special Interest (NOSI): Identification of Biomarkers of HIV Pathogenesis and Substance Use Disorder Comorbidity

NOFO Number

Release Date

03/31/2021

Expiration Date

Expiration Date

09/08/2024

Type of Award

Clinical Trials

Clinical Trial Optional

Organizations

Categories

Infectious Disease,

Methods Development

Archived

Yes

HEAL Initiative: Integrative Management of chronic Pain and OUD for Whole Recovery (IMPOWR): Research Centers (RM1 Clinical Trial Required)

NOFO Number

Release Date

01/11/2021

Expiration Date

Expiration Date

03/27/2021

Type of Award

Clinical Trials

Clinical Trial Optional

Organizations

Categories

Other Health Conditions,

Big Data Science,

Methods Development,

Dissemination and Implementation,

Archived

Yes

Notice of Special Interest (NOSI): Human Molecular Genetics of Substance Use Disorders

NOFO Number

Release Date

03/05/2020

Expiration Date

Expiration Date

09/08/2023

Type of Award

Clinical Trials

Clinical Trial Required,

Clinical Trial Not Allowed,

Basic Experimental Studies with Humans (BESH) Required,

Clinical Trial Optional

Organizations

Categories

Other Health Conditions,

Methods Development,

Systems Science,

Big Data Science

Archived

Yes