NIH: Office of Disease Prevention

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Implementation projects are used to apply an intervention in a community at large and measure the public health impact. The emphasis is on the external validity of the intervention, or whether or not the intervention can be used and is effective when implemented by others. This phase also involves quality control measures and determines if the intervention is being implemented as designed.

  • Disseminating Evidence-Based Interventions to Control Cancer
    National Cancer Institute (NCI)
    Evidence-based programs and policies can result in population-level reductions in premature cancer morbidity and mortality. Among real world public health audiences, there is limited knowledge regarding effective approaches for dissemination of research-tested interventions. The goal of this project is to increase the dissemination of evidence-based programs and policies to control cancer.
  • Conceptualizing the Problem of Implementation: A Systems Engineering Perspective Applied in Substance Abuse Treatment
    National Institute on Drug Abuse (NIDA)
    The project's goal is to apply the multi-attribute utility theory (which considers the process of implementation as a series of decisions made under uncertainty by stakeholders with potentially divergent values) to assess the perceived value of an evidence-based practice (EBP) for addiction treatment from the perspective of key health care stakeholders, and use it as a basis to identify and mitigate potential causes of EBP implementation failure.
  • Long-Term Effects of Communities That Care (CTC) on Young Adults From Small Towns
    National Institute on Drug Abuse (NIDA)
    CTC is a coalition-based prevention program run by the U.S. government that targets youth problem behaviors. The purpose of this research is to investigate the long-term effects of the CTC on young adult substance use and misuse, crime, violence, and incarceration 11 and 13 years following CTC's initial installation.
  • Evaluating Standardized Preventive Care to Reduce Dental Disparities in Children
    National Institute of Dental and Craniofacial Research (NIDCR)
    The Willamette Dental Group (WDG) program is a caries prevention program consisting of highly standardized, diagnosis-driven, risk-based, evidenced-based, clinical-decision-supported care documented in detail in an electronic health record. The objective of this study is to evaluate the WDG program's capacity to reduce disparities in caries burden between commercially insured and Medicaid-insured children.
  • Diabetes Prevention Program Outcomes Study
    National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
    National Institute on Aging (NIA)
    National Heart Lung and Blood Institute (NHLBI)
    National Eye Institute (NEI)

    The purpose of this study is to demonstrate that a lifestyle intervention program aimed at weight loss, along with certain medications, can prevent the onset of diabetes over a 10-year period. This study will also examine the impact of diabetes prevention on long-term complications affecting the nervous system and certain organs of the body.
  • Leadership and Organizational Change for Implementation Intervention in Substance Abuse Treatment Programs
    National Institute on Drug Abuse (NIDA)
    Leadership development approaches are often not based on empirically supported approaches and curricula, nor are they specifically designed for implementation of evidence-based programs (EBPs). This project tests the effects of an intervention to improve general and implementation leadership and utilize organizational strategies to create a positive strategic organizational climate for EBP implementation.
  • Adapting the Diabetes Prevention Program (DPP) for a Developing World Context
    National Heart, Lung, and Blood Institute (NHLBI)
    In the United States, evidence indicates that the DPP can enable overweight individuals to change their diet and physical activity levels and reduce their risk for diabetes and cardiovascular diseases. The purpose of this proposal is to adapt the DPP and evaluate its feasibility and effectiveness in an urban settlement community in South Africa.
  • Advancing Community-Based Participatory Research Practice through a Collective Reflection and Measurement Kit
    National Institute of Nursing Research (NINR)
    Despite the rapid growth of Community-Engaged Research (CEnR), a shared measurement and evaluation science is still minimal. This project refines and tests evidence-based measures and tools of CEnR partnering processes and outcomes in relation to national CEnR partnerships.