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Introduction

Tobacco use is the single most preventable cause of death and disease in the United States. Each year, approximately 443,000 Americans die from tobacco-related illnesses. For every person who dies from tobacco use, 20 more people suffer with at least 1 serious tobacco-related illness. In addition, tobacco use costs the U.S. $193 billion annually in direct medical expenses and lost productivity. [Cited from Healthy People 2020]

The NIH awards grants to support a variety of research projects related to tobacco use prevention, including projects in regulatory science, cancer prevention, and behavioral studies. This Research Highlight on tobacco use provides a sampling of funded research activities across the NIH, examples of recent scientific advances, and a selection of resources from both NIH and federal partners.