The National Cancer Institute is hosting this training institute to provide participants with a thorough grounding in conducting D&I research with a specific focus on cancer, across the cancer control continuum. In 2020, the institute will use a combination of online coursework (six modules with related assignments) and a 2-day in-person training to be held August 3 and 4, 2020, at the NCI campus in Bethesda, MD. Faculty and guest lecturers consist of leading experts in D&I theories, models, and frameworks; intervention fidelity and adaptation; stakeholder engagement and partnership for D&I; research methods and study designs for D&I; and measures and outcomes for D&I. This training institute has been adapted from the broader Training Institute for Dissemination and Implementation Research in Health (TIDIRH), organized by NIH and the VA over the past nine years.
This training is designed for investigators at any career stage interested in conducting D&I research with a focus on the cancer control continuum. There is no cost associated with the training. Invited participants are required to cover related travel expenses to the Washington D.C. area for the in-person meeting. More answers to common questions can be found on the site FAQ.
In this Methods: Mind the Gap webinar, Dr. William Vollmer provides some examples of the types of prevention activities that can be fostered using the Electronic Medical Record (EMR), offers some historical perspective on the challenges of using the EMR to conduct research more generally, and gives specific examples of prevention-oriented research that heavily relies on the EMR for its conduct.
Use of Theory in Implementation Research; Pragmatic Application and Scientific Advancement of the Consolidated Framework for Implementation Research (CFIR)
Dr. Laura Damschroder’s webinar introduces Consolidated Framework for Implementation Research (CFIR) and its application in a series of studies highlighting its use to guide data collection, analyses, and its potential for syntheses; and to guide tailoring of implementation strategies.
Use of Theory in Implementation Research; The Exploration, Preparation, Implementation, Sustainment (EPIS) Framework: A Phased and Multilevel Approach to Implementation
Dr. Greg Aarons’ webinar introduces the Exploration, Preparation, Implementation, Sustainment (EPIS) framework and its application in a series of studies highlighting its use to guide data collection, analyses, and its potential for syntheses; and to guide tailoring of implementation strategies.
Use of Theory in Implementation Research; Using the Interactive Systems Framework as a Lens for Readiness in Cancer Control?
Dr. Abe Wandersman’s webinar continued a series of presentations and discussions about the development and application of frequently-used implementation research models and frameworks. Dr. Wandersman, key developer of the Interactive Systems Framework (ISF), discusses the genesis of the framework, key terms and concepts, and then presents projects that have used the ISF as a core lens to support planning and study of evidence-based practice implementation.
Use of Theory in Implementation Research: Pragmatic Application and Scientific Advancement of the Knowledge-to-Action (KTA) Cycle
Dr. Sharon Straus, one of the primary authors of the Knowledge to Action Framework (KTA), discusses the genesis of the framework, key stages within the cycle, challenges to knowledge translation, and then presents examples of how the KTA framework has been used within a range of projects. Dr. Straus’ presentation also concentrates on the specific challenge of studying sustainability, and reflects on the degree to which the framework can extend beyond research into clinical practice use.
In this Methods: Mind the Gap presentation, Dr. Hekler first reviews the need for optimization of adaptive interventions, building on MOST, followed by an overview of control systems engineering and attributes of problems that are well matched to control engineering. He then summarizes key steps in the development and optimization of an adaptive intervention using this approach, leading to a COT.
In this Methods: Mind the Gap presentation, Dr. Klasnja describes how micro-randomized trials can be used to make data-driven decisions about how exactly individual components of mHealth interventions should work to optimize their effectiveness. He argues that a key value of micro-randomized trials during intervention development is their ability to generate data for informing decisions about the many specifics—from the design of the interface to the adaptation algorithms—that must be determined to implement an mHealth intervention. Data from micro-randomized trials enable such decisions to be made in ways that maximize intervention effectiveness while minimizing user burden.
This Methods: Mind the Gap webinar explores gene regulatory networks. Dr. Quackenbush shows multiple examples of gene regulatory networks, drawing on his work in cancer, chronic obstructive pulmonary disease, and the analysis of data from 38 tissues provided by the Genotype-Tissue Expression (GTEx) project.
In this Methods: Mind the Gap webinar, Dr. Siobhan Phillips provides an overview of how digital health tools can be used to better understand and optimize physical activity promotion interventions.
Implementation science methodologies, approaches, and tools have a great interdisciplinary applicability. Dr. Alice Ammerman’s webinar discusses what new (and "new to") D&I investigators need to know to succeed in this burgeoning field.
Dr. Geoffrey Curran’s presentation addresses the topic of hybrid effectiveness-implementation studies, a set of approaches to simultaneously studying the effectiveness of health interventions and the strategies to implement them in community and clinical practice settings. His presentation unpacks the rationale for these designs, a typology of designs based on the state of science for a given intervention, and provides examples of studies utilizing these important methods.