A collection of online chapters that provide an introduction to selected behavioral and social science research approaches, including theory development and testing, survey methods, measurement, and study design. eSource was developed in 2010, and these chapters have not been updated to reflect advances in the past decade. However, they can still be used as supplementary teaching materials.
This archive provides a collection of webinars on methodology. The topics include HIV prevention, implementation methods, personalized medicine, complexity, and longitudinal data. In 2017, the Office of Disease Prevention (ODP) provided co-funding to the Center for Prevention Implementation Methodology to help create this archive.
In this Methods: Mind the Gap presentation, Dr. Valerie Earnshaw provides a cross-cutting conceptual overview of stigma, identifies targets for stigma measurement, recommends methodological approaches for stigma research, and reviews the intervention toolkit to address stigma. She draws on examples from her own and others’ research, with a focus on two highly stigmatized disease contexts: HIV and substance use. She advocates for theory-based cross-cutting research to improve understanding of stigma and the development of intersectional, multilevel, and longitudinal interventions to enhance efforts to address stigma.
The NIH-Duke Master's Program in Clinical Research, established in 1998, is one of the nation's first training programs in clinical research. This program allows participants to attend formal courses in research design, research management, medical genomics, and statistical analysis at the Clinical Center by means of video-conferencing from Duke or on-site by adjunct faculty.
The program leads to a Master of Health Sciences in Clinical Research, a professional degree awarded by the Duke University School of Medicine. There is also a non-degree option for qualified students who want to pursue specific areas of interest.
Applications will be accepted through August 1, 2020.
In this Methods: Mind the Gap presentation, Dr. Rivera discusses the relevance of control engineering to mHealth using two interventions currently under development—Just Walk, an intervention to promote walking in sedentary adults, and Healthy Mom Zone, an intervention for managing gestational weight gain in overweight/obese pregnant women.
Arizona State University
In this Methods: Mind the Gap webinar, Dr. Linda Collins discusses why behavioral interventions are important in many areas of public health, for example, smoking cessation, drug abuse prevention, treatment of obesity, management of heart failure symptoms, and promotion of physical activity.
Behavioral interventions are typically developed and evaluated using a treatment package approach, in which the intervention is assembled a priori and evaluated by means of a randomized controlled trial (RCT). Dr. Collins reviews an alternative approach called the Multiphase Optimization Strategy (MOST), an engineering-inspired framework for developing, optimizing, and evaluating behavioral interventions. MOST includes the RCT, as well as other empirical steps aimed at intervention optimization.
The objective of this course is to provide a thorough grounding in the conduct of randomized clinical trials to researchers and health professionals interested in developing competence in the planning, design, and execution of randomized clinical trials involving behavioral interventions.
The curriculum will enable participants to:
- Describe the principles underlying the conduct of unbiased clinical trials
- Identify the unique challenges posed by behavioral randomized clinical trials (RCTs)
- Evaluate RCT designs in terms of their appropriateness to scientific and clinical goals
- Select appropriate strategies for enrollment, randomization, and retention of participants
- Understand methods for monitoring, coordinating, and conducting RCTs
- Develop strategies for appropriate statistical analyses of RCT data
- Evaluate the quality of behavioral RCTs and interpret their results
- Design an RCT as part of a working group on a specific topic.
Dr. Sterman discusses systems approaches in public health, including the concepts of policy resistance, implementation feedbacks, and model boundaries and explores how these ideas can be applied to effect change in a complex system. He includes examples from healthcare and public health such as implementation of formulary drug lists and SARS epidemic modeling.
Dr. McLeroy discusses adoption of systems methodology, including multiple levels of analysis, utility for identifying points of change, testing models against reality, and applications to program evaluation and various research designs, including community-based participatory research and randomized clinical trials.
In this Methods: Mind the Gap presentation, Dr. Klasnja describes how micro-randomized trials can be used to make data-driven decisions about how exactly individual components of mHealth interventions should work to optimize their effectiveness. He argues that a key value of micro-randomized trials during intervention development is their ability to generate data for informing decisions about the many specifics—from the design of the interface to the adaptation algorithms—that must be determined to implement an mHealth intervention. Data from micro-randomized trials enable such decisions to be made in ways that maximize intervention effectiveness while minimizing user burden.